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Only studies published in the last 5 years (20192024) were considered eligible

This result confirmed that (1) the assay detects endogenous LOXs activity in cells, (2) extracellular incorporation of BHZ corresponds to the presence of total activity of LOXs in the extracellular space, and 3) LOXL2 depletion results in a significant loss of total LOXs activity in HASMC

This triple-agonist mechanism is what makes it potentially more effective than single-agonist peptides like semaglutide , but it also means the gastrointestinal side effects can be more intense if you start too high

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